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Fungal prion HET-s as a model for structural complexity and self-propagation in prions

The highly ordered and reproducible structure of the fungal prion HET-s makes it an excellent model system for studying the inherent properties of prions, self-propagating infectious proteins that have been implicated in a number of fatal diseases. In particular, the HET-s prion-forming domain readi...

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Autori principali: Wan, William, Stubbs, Gerald
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986130/
https://ncbi.nlm.nih.gov/pubmed/24706820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322933111
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