Attenuation of Pathogenic Immune Responses during Infection with Human and Simian Immunodeficiency Virus (HIV/SIV) by the Tetracycline Derivative Minocycline

HIV immune pathogenesis is postulated to involve two major mechanisms: 1) chronic innate immune responses that drive T cell activation and apoptosis and 2) induction of immune regulators that suppress T cell function and proliferation. Both arms are elevated chronically in lymphoid tissues of non-na...

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Hlavní autoři: Drewes, Julia L., Szeto, Gregory L., Engle, Elizabeth L., Liao, Zhaohao, Shearer, Gene M., Zink, M. Christine, Graham, David R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986096/
https://ncbi.nlm.nih.gov/pubmed/24732038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094375
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