Immunization with a live, attenuated simian immunodeficiency virus (SIV) prevents early disease but not infection in rhesus macaques challenged with pathogenic SIV.

An infectious, virulence-attenuated molecular clone of simian immunodeficiency virus (SIV), SIVMAC-1A11, was derived from an SIV isolate that causes fatal immunodeficiency in rhesus macaques. When inoculated intravenously in rhesus macaques, SIVMAC-1A11 induced transient viremia (1 to 6 weeks) witho...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Marthas, M L, Sutjipto, S, Higgins, J, Lohman, B, Torten, J, Luciw, P A, Marx, P A, Pedersen, N C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249663/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2164591/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.8.3694-3700.1990
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