Immunization with a live, attenuated simian immunodeficiency virus (SIV) prevents early disease but not infection in rhesus macaques challenged with pathogenic SIV.

An infectious, virulence-attenuated molecular clone of simian immunodeficiency virus (SIV), SIVMAC-1A11, was derived from an SIV isolate that causes fatal immunodeficiency in rhesus macaques. When inoculated intravenously in rhesus macaques, SIVMAC-1A11 induced transient viremia (1 to 6 weeks) witho...

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Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Marthas, M L, Sutjipto, S, Higgins, J, Lohman, B, Torten, J, Luciw, P A, Marx, P A, Pedersen, N C
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1990
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249663/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2164591/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.8.3694-3700.1990
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