Replication-Competent Simian Immunodeficiency Virus (SIV) Gag Escape Mutations Archived in Latent Reservoirs during Antiretroviral Treatment of SIV-Infected Macaques

In response to pressure exerted by major histocompatibility complex (MHC) class I-mediated CD8(+) T cell control, human immunodeficiency virus (HIV) escape mutations often arise in immunodominant epitopes recognized by MHC class I alleles. While the current standard of care for HIV-infected patients...

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Détails bibliographiques
Auteurs principaux: Queen, Suzanne E., Mears, Brian M., Kelly, Kathleen M., Dorsey, Jamie L., Liao, Zhaohao, Dinoso, Jason B., Gama, Lucio, Adams, Robert J., Zink, M. Christine, Clements, Janice E., Kent, Stephen J., Mankowski, Joseph L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165835/
https://ncbi.nlm.nih.gov/pubmed/21715484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00366-11
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