Strictly Conserved Lysine of Prolyl-tRNA Synthetase Editing Domain Facilitates Binding and Positioning of Misacylated tRNA(Pro)

[Image: see text] To ensure high fidelity in translation, many aminoacyl-tRNA synthetases, enzymes responsible for attaching specific amino acids to cognate tRNAs, require proof-reading mechanisms. Most bacterial prolyl-tRNA synthetases (ProRSs) misactivate alanine and employ a post-transfer editing...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bartholow, Thomas G., Sanford, Brianne L., Cao, Bach, Schmit, Heidi L., Johnson, James M., Meitzner, Jet, Bhattacharyya, Sudeep, Musier-Forsyth, Karin, Hati, Sanchita
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986007/
https://ncbi.nlm.nih.gov/pubmed/24450765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401279r
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky