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Editing Domain Motions Preorganize the Synthetic Active Site of Prolyl-tRNA Synthetase
Prolyl-tRNA synthetases (ProRSs) catalyze the covalent attachment of proline onto cognate tRNAs, an indispensable step for protein synthesis in all living organisms. ProRSs are modular enzymes and the “prokaryotic-like” ProRSs are distinguished from “eukaryotic-like” ProRSs by the presence of an edi...
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| Publicado en: | ACS Catal |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8293909/ https://ncbi.nlm.nih.gov/pubmed/34295570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.0c02381 |
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