Editing Domain Motions Preorganize the Synthetic Active Site of Prolyl-tRNA Synthetase

Prolyl-tRNA synthetases (ProRSs) catalyze the covalent attachment of proline onto cognate tRNAs, an indispensable step for protein synthesis in all living organisms. ProRSs are modular enzymes and the “prokaryotic-like” ProRSs are distinguished from “eukaryotic-like” ProRSs by the presence of an edi...

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Publicat a:ACS Catal
Autors principals: Hu, Quin H., Williams, Murphi T., Shulgina, Irina, Fossum, Carl J., Weeks, Katelyn M., Adams, Lauren M., Reinhardt, Clorice R., Musier-Forsyth, Karin, Hati, Sanchita, Bhattacharyya, Sudeep
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8293909/
https://ncbi.nlm.nih.gov/pubmed/34295570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.0c02381
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