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Total Syntheses of (−)-Kopsifoline D and (−)-Deoxoapodine: Divergent Total Synthesis via Late-Stage Key Strategic Bond Formation

[Image: see text] Divergent total syntheses of (−)-kopsifoline D and (−)-deoxoapodine are detailed from a common pentacyclic intermediate 15, enlisting the late-stage formation of two different key strategic bonds (C21–C3 and C21–O–C6) unique to their hexacyclic ring systems that are complementary t...

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Detalhes bibliográficos
Main Authors: Lee, Kiyoun, Boger, Dale L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985950/
https://ncbi.nlm.nih.gov/pubmed/24499015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500548e
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