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A Strategy for the Late-Stage Divergent Syntheses of Scyphostatin Analogues

[Image: see text] This account details the synthesis of two scyphostatin analogues exhibiting a reactive polar epoxycyclohexenone core and various amide side chains outfitted for late-stage chemical derivatization into the desirable lipophilic tails. Our efforts highlight a key ipso-dearomatization...

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Main Authors: Cha, Jacob Y., Burnett, G. Leslie, Huang, Yaodong, Davidson, Jarrod B., Pettus, Thomas R. R.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071563/
https://ncbi.nlm.nih.gov/pubmed/21250721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo102327e
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