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Design of Sequence-Specific DNA Binding Molecules for DNA Methyltransferase Inhibition
[Image: see text] The CpG dyad, an important genomic feature in DNA methylation and transcriptional regulation, is an attractive target for small molecules. To assess the utility of minor groove binding oligomers for CpG recognition, we screened a small library of hairpin pyrrole-imidazole polyamide...
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| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2014
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985849/ https://ncbi.nlm.nih.gov/pubmed/24502234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500211z |
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