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Design of Sequence-Specific DNA Binding Molecules for DNA Methyltransferase Inhibition
[Image: see text] The CpG dyad, an important genomic feature in DNA methylation and transcriptional regulation, is an attractive target for small molecules. To assess the utility of minor groove binding oligomers for CpG recognition, we screened a small library of hairpin pyrrole-imidazole polyamide...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2014
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985849/ https://ncbi.nlm.nih.gov/pubmed/24502234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500211z |
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