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Glycosylation of Skp1 Affects Its Conformation and Promotes Binding to a Model F-Box Protein

[Image: see text] In the social amoeba Dictyostelium, Skp1 is hydroxylated on proline 143 and further modified by three cytosolic glycosyltransferases to yield an O-linked pentasaccharide that contributes to O(2) regulation of development. Skp1 is an adapter in the Skp1/cullin1/F-box protein family...

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Autors principals: Sheikh, M. Osman, Schafer, Christopher M., Powell, John T., Rodgers, Karla K., Mooers, Blaine H. M., West, Christopher M.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985704/
https://ncbi.nlm.nih.gov/pubmed/24506136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401707y
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