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Structural and Thermodynamical Insights into the Recognition of Native Proteins by Anti-Peptide Antibodies

The mechanism by which antibodies elicited against protein-derived peptides achieve cross-reactivity with their cognate proteins remains unknown. To address this question we have carried out the complete thermodynamic characterization of the association of a monoclonal antibody (260.33.12) raised ag...

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Detalhes bibliográficos
Main Authors: Armstrong, A. A., Hildreth, James E. K., Amzel, L. M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985606/
https://ncbi.nlm.nih.gov/pubmed/23473830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.02.031
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