Effects of Enzymatically Inactive Recombinant Botulinum Neurotoxin Type A at the Mouse Neuromuscular Junctions

Botulinum neurotoxin A (BoNT/A) is used clinically to treat several neurological and metabolic diseases. However, the mechanisms that underlie the clinical use of the toxin remain still to be elusive. BoNT/A inhibits acetylcholine (ACh) release at the motor nerve terminals (MNT) and causes neuropara...

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Autori principali: Baskaran, Padmamalini, Lehmann, Teresa E., Topchiy, Elena, Thirunavukkarasu, Nagarajan, Cai, Shuowei, Singh, Bal Ram, Deshpande, Sharad, Thyagarajan, Baskaran
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985282/
https://ncbi.nlm.nih.gov/pubmed/23810945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2013.06.014
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