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Capsaicin Protects Mouse Neuromuscular Junctions from the Neuroparalytic Effects of Botulinum Neurotoxin A

Botulinum neurotoxin A (BoNT/A), the most toxic, naturally occurring protein, cleaves synapse-associated protein of 25 kDa and inhibits acetylcholine release from motor nerve endings (MNEs). This leads to paralysis of skeletal muscles. Our study demonstrates that capsaicin protects mouse neuromuscul...

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Detalhes bibliográficos
Main Authors: Thyagarajan, Baskaran, Krivitskaya, Natalia, Potian, Joseph G., Hognason, Kormakur, Garcia, Carmen C., McArdle, Joseph J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775269/
https://ncbi.nlm.nih.gov/pubmed/19654265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.156901
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