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A Single Direct Injection into the Left Ventricular Wall of an AAV9 Vector Expressing EcSOD from the Cardiac Troponin-T Promoter Protects Mice Against Myocardial Infarction

BACKGROUND: Localized administration of a highly efficient gene delivery system in combination with a cardiac-selective promoter may provide an adequate biosafety profile in clinical applications such as coronary artery bypass graft surgery (CABG), where regions of myocardium can be readily injected...

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Detalhes bibliográficos
Main Authors: Prasad, Konkal-Matt R., Smith, Robert S., Xu, Yaqin, French, Brent A
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984922/
https://ncbi.nlm.nih.gov/pubmed/21674736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.1576
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