Cardiac-Selective Expression of EcSOD After Systemic Injection of AAV9 Protects the Heart Against Post-MI LV Remodeling

BACKGROUND: Cardiac magnetic resonance (CMR) imaging has not previously been used to document the attenuation of LV remodeling after systemic gene delivery. We hypothesized that targeted expression of extracellular superoxide dismutase (EcSOD) via the cardiac Troponin-T (cTnT) promoter would protect...

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Detalhes bibliográficos
Main Authors: Konkalmatt, Prasad R., Beyers, Ronald J., O'Connor, Daniel M., Xu, Yaqin, Seaman, Marc E., French, Brent A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762576/
https://ncbi.nlm.nih.gov/pubmed/23536266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCIMAGING.112.000320
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