Development of neutralizing scFv-Fc against botulinum neurotoxin A light chain from a macaque immune library

Botulinum toxins (BoNTs) are among the most toxic substances on earth, with serotype A toxin being the most toxic substance known. They are responsible for human botulism, a disease characterized by flaccid muscle paralysis that occurs naturally through food poisoning or the colonization of the gast...

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Huvudupphovsmän: Miethe, Sebastian, Rasetti-Escargueil, Christine, Liu, Yvonne, Chahboun, Siham, Pelat, Thibaut, Avril, Arnaud, Frenzel, Andrè, Schirrmann, Thomas, Thullier, Philippe, Sesardic, Dorothea, Hust, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984333/
https://ncbi.nlm.nih.gov/pubmed/24492304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.27773
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