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Isolation of nanomolar scFvs of non-human primate origin, cross-neutralizing botulinum neurotoxins A(1) and A(2) by targeting their heavy chain

BACKGROUND: Botulism is a naturally occurring disease, mainly caused by the ingestion of food contaminated by the botulinum neurotoxins (BoNTs). Botulinum neurotoxins are the most lethal. They are classified among the six major biological warfare agents by the Centers for Disease Control. BoNTs act...

詳細記述

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書誌詳細
出版年:BMC Biotechnol
主要な著者: Avril, Arnaud, Miethe, Sebastian, Popoff, Michel R., Mazuet, Christelle, Chahboun, Siham, Rasetti-Escargueil, Christine, Sesardic, Dorothea, Thullier, Philippe, Hust, Michael, Pelat, Thibaut
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574468/
https://ncbi.nlm.nih.gov/pubmed/26382731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-015-0206-0
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