Isolation of nanomolar scFvs of non-human primate origin, cross-neutralizing botulinum neurotoxins A(1) and A(2) by targeting their heavy chain

BACKGROUND: Botulism is a naturally occurring disease, mainly caused by the ingestion of food contaminated by the botulinum neurotoxins (BoNTs). Botulinum neurotoxins are the most lethal. They are classified among the six major biological warfare agents by the Centers for Disease Control. BoNTs act...

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Detalhes bibliográficos
Publicado no:BMC Biotechnol
Main Authors: Avril, Arnaud, Miethe, Sebastian, Popoff, Michel R., Mazuet, Christelle, Chahboun, Siham, Rasetti-Escargueil, Christine, Sesardic, Dorothea, Thullier, Philippe, Hust, Michael, Pelat, Thibaut
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574468/
https://ncbi.nlm.nih.gov/pubmed/26382731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-015-0206-0
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