The cyclin-dependent kinase inhibitor p57(Kip2) mediates proliferative actions of PTHrP in chondrocytes

Parathyroid hormone–related peptide (PTHrP) is a positive regulator of chondrocyte proliferation during bone development. In embryonic mice lacking PTHrP, chondrocytes stop proliferating prematurely, with accelerated differentiation. Because the bone phenotype of mice lacking the cyclin-dependent ki...

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Dades bibliogràfiques

Publicat a:	J Clin Invest
Autors principals:	MacLean, Helen E., Guo, Jun, Knight, Melissa C., Zhang, Pumin, Cobrinik, David, Kronenberg, Henry M.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Clinical Investigation 2004
Matèries:	Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398433/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15124025/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI21252
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