The cyclin-dependent kinase inhibitor p57(Kip2) mediates proliferative actions of PTHrP in chondrocytes

Parathyroid hormone–related peptide (PTHrP) is a positive regulator of chondrocyte proliferation during bone development. In embryonic mice lacking PTHrP, chondrocytes stop proliferating prematurely, with accelerated differentiation. Because the bone phenotype of mice lacking the cyclin-dependent ki...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	J Clin Invest
Hauptverfasser:	MacLean, Helen E., Guo, Jun, Knight, Melissa C., Zhang, Pumin, Cobrinik, David, Kronenberg, Henry M.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 2004
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398433/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15124025/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI21252
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!