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Cis-regulatory elements are harbored in Intron5 of the RUNX1 gene

BACKGROUND: Human RUNX1 gene is one of the most frequent target for chromosomal translocations associated with acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL). The highest prevalence in AML is noted with (8; 21) translocation; which represents 12 to 15% of all AML cases. Interestingly...

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Hlavní autoři: Rebolledo-Jaramillo, Boris, Alarcon, Ricardo A, Fernandez, Valentina I, Gutierrez, Soraya E
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984029/
https://ncbi.nlm.nih.gov/pubmed/24655352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-225
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