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Cis-regulatory elements are harbored in Intron5 of the RUNX1 gene

BACKGROUND: Human RUNX1 gene is one of the most frequent target for chromosomal translocations associated with acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL). The highest prevalence in AML is noted with (8; 21) translocation; which represents 12 to 15% of all AML cases. Interestingly...

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Detalhes bibliográficos
Main Authors: Rebolledo-Jaramillo, Boris, Alarcon, Ricardo A, Fernandez, Valentina I, Gutierrez, Soraya E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984029/
https://ncbi.nlm.nih.gov/pubmed/24655352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-225
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