Use of Induced Pluripotent Stem Cells to Recapitulate Pulmonary Alveolar Proteinosis Pathogenesis

Rationale: In patients with pulmonary alveolar proteinosis (PAP) syndrome, disruption of granulocyte/macrophage colony–stimulating factor (GM-CSF) signaling is associated with pathogenic surfactant accumulation from impaired clearance in alveolar macrophages. Objectives: The aim of this study was to...

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Detalhes bibliográficos
Main Authors: Suzuki, Takuji, Mayhew, Christopher, Sallese, Anthony, Chalk, Claudia, Carey, Brenna C., Malik, Punam, Wood, Robert E., Trapnell, Bruce C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983889/
https://ncbi.nlm.nih.gov/pubmed/24279752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201306-1039OC
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