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Conditional Deletions of Epilepsy-Associated KCNQ2 and KCNQ3 Channels from Cerebral Cortex Cause Differential Effects on Neuronal Excitability

KCNQ2 and KCNQ3 potassium channels have emerged as central regulators of pyramidal neuron excitability and spiking behavior. However, despite an abundance of evidence demonstrating that KCNQ2/3 heteromers underlie critical potassium conductances, it is unknown whether KCNQ2, KCNQ3, or both are oblig...

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Detalles Bibliográficos
Autores principales: Soh, Heun, Pant, Rima, LoTurco, Joseph J., Tzingounis, Anastasios V.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983807/
https://ncbi.nlm.nih.gov/pubmed/24719109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3919-13.2014
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