Deletion of KCNQ2/3 potassium channels from PV+ interneurons leads to homeostatic potentiation of excitatory transmission

KCNQ2/3 channels, ubiquitously expressed neuronal potassium channels, have emerged as indispensable regulators of brain network activity. Despite their critical role in brain homeostasis, the mechanisms by which KCNQ2/3 dysfunction lead to hypersychrony are not fully known. Here, we show that deleti...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Soh, Heun, Park, Suhyeorn, Ryan, Kali, Springer, Kristen, Maheshwari, Atul, Tzingounis, Anastasios V
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2018
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211828/
https://ncbi.nlm.nih.gov/pubmed/30382937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38617
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