Epilepsy-Associated KCNQ2 Channels Regulate Multiple Intrinsic Properties of Layer 2/3 Pyramidal Neurons

KCNQ2 potassium channels are critical for normal brain function, as both loss-of-function and gain-of-function KCNQ2 variants can lead to various forms of neonatal epilepsy. Despite recent progress, the full spectrum of consequences as a result of KCNQ2 dysfunction in neocortical pyramidal neurons i...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Niday, Zachary, Hawkins, Virginia E., Soh, Heun, Mulkey, Daniel K., Tzingounis, Anastasios V.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2017
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242407/
https://ncbi.nlm.nih.gov/pubmed/28100740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1425-16.2016
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