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Codon-dependent conformational change of elongation factor Tu preceding GTP hydrolysis on the ribosome.

The mechanisms by which elongation factor Tu (EF-Tu) promotes the binding of aminoacyl-tRNA to the A site of the ribosome and, in particular, how GTP hydrolysis by EF-Tu is triggered on the ribosome, are not understood. We report steady-state and time-resolved fluorescence measurements, performed in...

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Auteurs principaux: Rodnina, M V, Fricke, R, Kuhn, L, Wintermeyer, W
Format: Artigo
Langue:Inglês
Publié: 1995
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC398375/
https://ncbi.nlm.nih.gov/pubmed/7781613
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