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Codon-dependent conformational change of elongation factor Tu preceding GTP hydrolysis on the ribosome.

The mechanisms by which elongation factor Tu (EF-Tu) promotes the binding of aminoacyl-tRNA to the A site of the ribosome and, in particular, how GTP hydrolysis by EF-Tu is triggered on the ribosome, are not understood. We report steady-state and time-resolved fluorescence measurements, performed in...

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Pubblicato in:EMBO J
Autori principali: Rodnina, M V, Fricke, R, Kuhn, L, Wintermeyer, W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1995
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398375/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7781613/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07259.x
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