Extensive interactions of PRP8 protein with the 5' and 3' splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA.

Lignende værker

• Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8
  af: Kershaw, Christopher J., et al.
  Udgivet: (2009)
• U5 snRNA Interactions With Exons Ensure Splicing Precision
  af: Artemyeva-Isman, Olga V., et al.
  Udgivet: (2021)
• snRNA interactions at 5' and 3' splice sites monitored by photoactivated crosslinking in yeast spliceosomes.
  af: Newman, A J, et al.
  Udgivet: (1995)
• The Prp18 protein stabilizes the interaction of both exons with the U5 snRNA during the second step of pre-mRNA splicing
  af: Crotti, Luciana B., et al.
  Udgivet: (2007)
• Prp8 positioning of U5 snRNA is linked to 5′ splice site recognition
  af: MacRae, Andrew J., et al.
  Udgivet: (2018)