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U5 snRNA Interactions With Exons Ensure Splicing Precision

Imperfect conservation of human pre-mRNA splice sites is necessary to produce alternative isoforms. This flexibility is combined with the precision of the message reading frame. Apart from intron-termini GU_AG and the branchpoint A, the most conserved are the exon-end guanine and +5G of the intron s...

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Publicado en:Front Genet
Main Authors: Artemyeva-Isman, Olga V., Porter, Andrew C. G.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283771/
https://ncbi.nlm.nih.gov/pubmed/34276781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.676971
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