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A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B.

The inducible, higher eukaryotic transcription factor NF-kappa B is activated by a variety of external stimuli including inflammatory cytokines, viral and bacterial infection and UV irradiation. Here we show that internal stress, caused by the accumulation of proteins in the endoplasmic reticulum (E...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Pahl, H L, Baeuerle, P A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1995
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398372/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7781611/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07256.x
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