FGF23 promotes renal calcium reabsorption through the TRPV5 channel

αKlotho is thought to activate the epithelial calcium channel Transient Receptor Potential Vanilloid-5 (TRPV5) in distal renal tubules through its putative glucuronidase/sialidase activity, thereby preventing renal calcium loss. However, αKlotho also functions as the obligatory co-receptor for fibro...

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Bibliografski detalji
Glavni autori: Andrukhova, Olena, Smorodchenko, Alina, Egerbacher, Monika, Streicher, Carmen, Zeitz, Ute, Goetz, Regina, Shalhoub, Victoria, Mohammadi, Moosa, Pohl, Elena E, Lanske, Beate, Erben, Reinhold G
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2014
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983685/
https://ncbi.nlm.nih.gov/pubmed/24434184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201284188
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