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FGF23 promotes renal calcium reabsorption through the TRPV5 channel
αKlotho is thought to activate the epithelial calcium channel Transient Receptor Potential Vanilloid-5 (TRPV5) in distal renal tubules through its putative glucuronidase/sialidase activity, thereby preventing renal calcium loss. However, αKlotho also functions as the obligatory co-receptor for fibro...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3983685/ https://ncbi.nlm.nih.gov/pubmed/24434184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201284188 |
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