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Genetic Ablation of Fgf23 or Klotho Does not Modulate Experimental Heart Hypertrophy Induced by Pressure Overload

Left ventricular hypertrophy (LVH) ultimately leads to heart failure in conditions of increased cardiac pre- or afterload. The bone-derived phosphaturic and sodium-conserving hormone fibroblast growth factor-23 (FGF23) and its co-receptor Klotho have been implicated in the development of uremic LVH....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Slavic, Svetlana, Ford, Kristopher, Modert, Magalie, Becirovic, Amarela, Handschuh, Stephan, Baierl, Andreas, Katica, Nejla, Zeitz, Ute, Erben, Reinhold G., Andrukhova, Olena
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595838/
https://ncbi.nlm.nih.gov/pubmed/28900153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10140-4
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