Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function.

ZAP-70 is a protein tyrosine kinase (PTK) required for T-cell development and T-cell antigen receptor (TCR) function. ZAP-70 is associated with the phosphorylated antigen receptor and undergoes tyrosine phosphorylation following receptor activation. We demonstrate here that tyrosine phosphorylation...

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Pubblicato in:	EMBO J
Autori principali:	Chan, A C, Dalton, M, Johnson, R, Kong, G H, Wang, T, Thoma, R, Kurosaki, T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398363/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7781602/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07247.x
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