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Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function.

ZAP-70 is a protein tyrosine kinase (PTK) required for T-cell development and T-cell antigen receptor (TCR) function. ZAP-70 is associated with the phosphorylated antigen receptor and undergoes tyrosine phosphorylation following receptor activation. We demonstrate here that tyrosine phosphorylation...

Täydet tiedot

Tallennettuna:
Julkaisussa:EMBO J
Päätekijät: Chan, A C, Dalton, M, Johnson, R, Kong, G H, Wang, T, Thoma, R, Kurosaki, T
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 1995
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398363/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7781602/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07247.x
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