Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function.

Eitemau Tebyg

• Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function.
  gan: Kong, G, et al.
  Cyhoeddwyd: (1996)
• Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation.
  gan: Williams, B L, et al.
  Cyhoeddwyd: (1999)
• Interdomain B in ZAP-70 Regulates but Is Not Required for ZAP-70 Signaling Function in Lymphocytes
  gan: Zhao, Qihong, et al.
  Cyhoeddwyd: (1999)
• Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance.
  gan: Bu, J Y, et al.
  Cyhoeddwyd: (1995)
• The CD3 chains of the T cell antigen receptor associate with the ZAP-70 tyrosine kinase and are tyrosine phosphorylated after receptor stimulation
  Cyhoeddwyd: (1993)