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Synapto-depressive effects of amyloid beta require PICK1

Amyloid beta (Aβ), a key component in the pathophysiology of Alzheimer’s disease, is thought to target excitatory synapses early in the disease. However, the mechanism by which Aβ weakens synapses is not well understood. Here we showed that the PDZ domain protein, protein interacting with C kinase 1...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Alfonso, Stephanie, Kessels, Helmut W., Banos, Charles C., Chan, Timothy R., Lin, Edward T., Kumaravel, Gnanasambandam, Scannevin, Robert H., Rhodes, Kenneth J., Huganir, Richard, Guckian, Kevin M., Dunah, Anthone W., Malinow, Roberto
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983572/
https://ncbi.nlm.nih.gov/pubmed/24713001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12499
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