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Assessing uncertainty in model parameters based on sparse and noisy experimental data

To perform parametric identification of mathematical models of biological events, experimental data are rare to be sufficient to estimate target behaviors produced by complex non-linear systems. We performed parameter fitting to a cell cycle model with experimental data as an in silico experiment. W...

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Detalhes bibliográficos
Main Authors: Hiroi, Noriko, Swat, Maciej, Funahashi, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983526/
https://ncbi.nlm.nih.gov/pubmed/24772089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00128
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