Unveiling the Membrane-Binding Properties of N-Terminal and C-Terminal Regions of G Protein-Coupled Receptor Kinase 5 by Combined Optical Spectroscopies

[Image: see text] G protein-coupled receptor kinase 5 (GRK5) is thought to associate with membranes in part via N- and C-terminal segments that are typically disordered in available high-resolution crystal structures. Herein we investigate the interactions of these regions with model cell membrane u...

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Main Authors: Ding, Bei, Glukhova, Alisa, Sobczyk-Kojiro, Katarzyna, Mosberg, Henry I., Tesmer, John J. G., Chen, Zhan
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983354/
https://ncbi.nlm.nih.gov/pubmed/24401145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la404055a
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