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Palladium-Catalyzed Amination of Unprotected Five-Membered Heterocyclic Bromides

[Image: see text] An efficient method for the palladium-catalyzed amination of unprotected bromoimidazoles and bromopyrazoles is presented. The transformation is facilitated by the use of our newly developed Pd precatalyst based on the bulky biarylphosphine ligand tBuBrettPhos (L4). The mild reactio...

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Detalhes bibliográficos
Main Authors: Su, Mingjuan, Hoshiya, Naoyuki, Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983327/
https://ncbi.nlm.nih.gov/pubmed/24417224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol4035947
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