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Palladium-Catalyzed Amination of Unprotected Five-Membered Heterocyclic Bromides

[Image: see text] An efficient method for the palladium-catalyzed amination of unprotected bromoimidazoles and bromopyrazoles is presented. The transformation is facilitated by the use of our newly developed Pd precatalyst based on the bulky biarylphosphine ligand tBuBrettPhos (L4). The mild reactio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Su, Mingjuan, Hoshiya, Naoyuki, Buchwald, Stephen L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983327/
https://ncbi.nlm.nih.gov/pubmed/24417224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol4035947
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