Affinity and specificity requirements for the first Src homology 3 domain of the Crk proteins.

The specificity of SH3 domain complex formation plays an important role in determining signal transduction events. We have previously identified a highly specific interaction between the first CrkSH3 domain [CrkSH3(1)] and proline-rich sequences in the guanine nucleotide exchange factor C3G. A 10 am...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Knudsen, B S, Zheng, J, Feller, S M, Mayer, J P, Burrell, S K, Cowburn, D, Hanafusa, H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398325/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7774577/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07213.x
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