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Affinity and specificity requirements for the first Src homology 3 domain of the Crk proteins.

The specificity of SH3 domain complex formation plays an important role in determining signal transduction events. We have previously identified a highly specific interaction between the first CrkSH3 domain [CrkSH3(1)] and proline-rich sequences in the guanine nucleotide exchange factor C3G. A 10 am...

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Autori principali: Knudsen, B S, Zheng, J, Feller, S M, Mayer, J P, Burrell, S K, Cowburn, D, Hanafusa, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC398325/
https://ncbi.nlm.nih.gov/pubmed/7774577
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