p150(glued)-Associated Disorders Are Caused by Activation of Intrinsic Apoptotic Pathway

Mutations in p150(glued) cause hereditary motor neuropathy with vocal cord paralysis (HMN7B) and Perry syndrome (PS). Here we show that both overexpression of p150(glued) mutants and knockdown of endogenous p150(glued) induce apoptosis. Overexpression of a p150(glued) plasmid containing either a HMN...

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Main Authors: Ishikawa, Kei-Ichi, Saiki, Shinji, Furuya, Norihiko, Yamada, Daisuke, Imamichi, Yoko, Li, Yuanzhe, Kawajiri, Sumihiro, Sasaki, Hironori, Koike, Masato, Tsuboi, Yoshio, Hattori, Nobutaka
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983229/
https://ncbi.nlm.nih.gov/pubmed/24722468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094645
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