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The pRB-related protein p107 contains two growth suppression domains: independent interactions with E2F and cyclin/cdk complexes.

Unregulated expression of either the retinoblastoma protein (pRB) or the related protein p107 can cause growth arrest of sensitive cells in the G1 phase of the cell cycle. However, growth arrests mediated by p107 and pRB are not identical. Through structure-function and co-expression analyses we hav...

詳細記述

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書誌詳細
主要な著者: Zhu, L, Enders, G, Lees, J A, Beijersbergen, R L, Bernards, R, Harlow, E
フォーマット: Artigo
言語:Inglês
出版事項: 1995
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC398289/
https://ncbi.nlm.nih.gov/pubmed/7743997
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