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Loss of pRB and p107 disrupts cartilage development and promotes enchondroma formation

The pocket proteins pRB, p107, and p130 have established roles in regulating the cell cycle through the control of E2F activity. The pocket proteins regulate differentiation of a number of tissues in both cell cycle-dependent and –independent manners. Prior studies showed that mutation of p107 and p...

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Autors principals: Landman, Allison S., Danielian, Paul S., Lees, Jacqueline A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931423/
https://ncbi.nlm.nih.gov/pubmed/23146901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.496
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