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Loss of pRB and p107 disrupts cartilage development and promotes enchondroma formation
The pocket proteins pRB, p107, and p130 have established roles in regulating the cell cycle through the control of E2F activity. The pocket proteins regulate differentiation of a number of tissues in both cell cycle-dependent and –independent manners. Prior studies showed that mutation of p107 and p...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3931423/ https://ncbi.nlm.nih.gov/pubmed/23146901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.496 |
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