Immuno-PET imaging of the hepatocyte growth factor receptor Met using the one-armed antibody Onartuzumab (MetMAb)

The over-expression and -activation of hepatocyte growth factor receptor (Met) in various cancers has been linked to increased proliferation, progression to metastatic disease, and drug resistance. Developing a PET imaging agent to assess Met expression would aid in diagnosis and monitoring response...

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Detalhes bibliográficos
Main Authors: Jagoda, Elaine M., Lang, Lixin, Bhadrasetty, Veerendra, Histed, Stephanie, Williams, Mark, Kramer-Marek, Gabriela, Mena, Esther, Rosenblum, Lauren, Marik, Jan, Tinianow, Jeffrey, Merchant, Mark, Szajek, Lawrence, Paik, Chang, Cecchi, Fabiola, Raffensperger, Kristen, Jose-Dizon, Joe-Marie, Bottaro, Donald P., Choyke, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982858/
https://ncbi.nlm.nih.gov/pubmed/22917884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.111.102293
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