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Immuno-PET imaging of the hepatocyte growth factor receptor Met using the one-armed antibody Onartuzumab (MetMAb)
The over-expression and -activation of hepatocyte growth factor receptor (Met) in various cancers has been linked to increased proliferation, progression to metastatic disease, and drug resistance. Developing a PET imaging agent to assess Met expression would aid in diagnosis and monitoring response...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3982858/ https://ncbi.nlm.nih.gov/pubmed/22917884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.111.102293 |
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