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Alphavirus-based Vaccines Encoding Nonstructural Proteins of Hepatitis C Virus Induce Robust and Protective T-cell Responses

An absolute prerequisite for a therapeutic vaccine against hepatitis C virus (HCV) infection is the potency to induce HCV-specific vigorous and broad-spectrum T-cell responses. Here, we generated three HCV vaccines based on a recombinant Semliki Forest virus (rSFV) vector expressing all- or a part o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ip, Peng Peng, Boerma, Annemarie, Regts, Joke, Meijerhof, Tjarko, Wilschut, Jan, Nijman, Hans W, Daemen, Toos
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982487/
https://ncbi.nlm.nih.gov/pubmed/24370701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.287
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