A rationally designed combined treatment with an alphavirus-based cancer vaccine, sunitinib and low-dose tumor irradiation completely blocks tumor development

The clinical efficacy of therapeutic cancer vaccines remains limited. For effective immunotherapeutic responses in cancer patients, multimodal approaches capable of both inducing antitumor immune responses and bypassing tumor-mediated immune escape seem essential. Here, we report on a combination th...

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Publicat a:Oncoimmunology
Autors principals: Draghiciu, Oana, Boerma, Annemarie, Hoogeboom, Baukje Nynke, Nijman, Hans W, Daemen, Toos
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589062/
https://ncbi.nlm.nih.gov/pubmed/26451295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1029699
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