A rationally designed combined treatment with an alphavirus-based cancer vaccine, sunitinib and low-dose tumor irradiation completely blocks tumor development

The clinical efficacy of therapeutic cancer vaccines remains limited. For effective immunotherapeutic responses in cancer patients, multimodal approaches capable of both inducing antitumor immune responses and bypassing tumor-mediated immune escape seem essential. Here, we report on a combination th...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Draghiciu, Oana, Boerma, Annemarie, Hoogeboom, Baukje Nynke, Nijman, Hans W, Daemen, Toos
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589062/
https://ncbi.nlm.nih.gov/pubmed/26451295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1029699
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