Transcriptional activation by Myc is under negative control by the transcription factor AP-2.

The Myc protein binds to and transactivates the expression of genes via E-box elements containing a central CAC(G/A)TG sequence. The transcriptional activation function of Myc is required for its ability to induce cell cycle progression, cellular transformation and apoptosis. Here we show that trans...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Gaubatz, S, Imhof, A, Dosch, R, Werner, O, Mitchell, P, Buettner, R, Eilers, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1995
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398238/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7729426/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07137.x
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